In recent years, an increasing amount of attention has been paid to medicinal products as possible risk factors in the development of eye diseases. The frequency of diagnosed drug-induced uveitis is growing yearly, which can be attributed to the appearance of new drugs - biological agents (immune checkpoint inhibitors, BRAF and MEK inhibitors, vascular endothelial growth factor inhibitors, tumor necrosis factor-α inhibitors), as well as systemic bisphosphonates and some antiviral drugs. The time interval between the beginning of the drug use and the appearance of uveitis symptoms varies from several days to months.
View Article and Find Full Text PDFDrug-induced optic neuropathy is a group of disorders in which medications cause degeneration of the optic nerve. The true prevalence of drug-induced neuropathy has not been studied, although the percentage of patients who develop optic nerve damage is known for individual medications. The common pathophysiological mechanisms are believed to be mitochondrial damage and imbalance of intracellular and extracellular free radical homeostasis.
View Article and Find Full Text PDFPurpose: To evaluate the properties of the microvasculature of bulbar conjunctiva and to assess the function of endothelium of the main arteries in type 1 diabetes mellitus (T1DM).
Material And Methods: The study included 35 patients with T1DM and initial nonproliferative diabetic retinopathy (NPDR). The control group consisted of 30 subjects.
Vestn Oftalmol
January 2015
Unlabelled: The aim was to study the state of microvascular bulbar conjunctiva in patients with type 1 diabetes.
Material And Methods: A clinical study of 25 patients with DR in the type 1 diabetes and 20 healthy persons without ophthalmopathology. All patients in addition to conventional methods of ophthalmological conducted computer Capillaroscopy bulbar conjunctiva.
The article presents the current data on seven main human herpesviruses, capable of causing ocular inflammation. Features of intraocular production and anterior segment involvement associated with each of the viruses and modern aspects of antiviral therapy for herpetic keratitis are discussed.
View Article and Find Full Text PDF