Publications by authors named "G Serfontein"

Behavioral and quantitative electroencephalography (EEG) techniques were used to evaluate treatment response to stimulant therapy in children with attention disorders. A sample of 130 children with attention disorders were evaluated with Conners and Diagnostic and Statistical Manual of Mental Disorders--III rating scales, and with neurometric quantitative EEG before and 6 to 14 months after treatment with stimulants. Significant quantitative EEG differences were found between the normal control population (N = 31) and the children with attention problems.

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Quantitative electroencephalogram (QEEG) was obtained from 407 children with attention deficit disorder. These QEEGs were compared to those of 310 normal children. Discriminant analysis resulted in a specificity of 88% and a sensitivity of 93.

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The sensitivity and specificity of QEEG-based discriminant functions were evaluated in populations of children diagnosed with specific developmental learning disorders and those with attention deficit disorders. Both populations of children could be distinguished from each other, and from the normal population, with high levels of accuracy. Pretreatment QEEG could be utilized to distinguish ADD/ADHD children who responded to dextroamphetamine from those who responded to methylphenidate, again with high levels of accuracy.

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Posterior fossa subdural hematoma formation in the newborn is an infrequently reported event. It is characterized by a complicated delivery, usually at term, followed by developing lethargy and irritability within the first few days of life. Respiratory irregularities, tense anterior fontanelle, and increasing head circumference ensue, accompanied by a falling hemoglobin and blood-stained cerebrospinal fluid.

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The early diagnosis of posterior fossa hematoma in three term infants by computed tomography is described. The clinical findings included difficult labor and delivery, sudden onset of apnea during the first 24 hours of life, tense bulging fontanel, falling hematocrit, bloody cerebrospinal fluid, and cerebral obtundation. Rapid operative removal of the clot resulted in good recovery in two of the infants.

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