Publications by authors named "G Sener"

Objective: In our study, the protective effect of dodder plant extract against encephalopathy induced by cholestatic liver disease model was investigated.

Methods: Spraque Dawley rats were used in the study. For the cholestatic liver disease model, the bile duct ligation (BDL) was applied.

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Introduction: Postmenopausal diabetes is a condition that affects millions of women and their quality of life. Also, kidney and small intestine tissues are damaged due to diabetes. The present study aimed to examine the protective effects of an extract prepared from leaves on kidney and small intestine tissues against experimentally created postmenopausal diabetes.

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Hypertension contributes to both the development and progression of brain damage and cognitive dysfunction in the postmenopausal period in women. Carvacrol (CAR), which can easily cross the blood-brain barrier, exhibits neuroprotective properties due to its antioxidant, anti-inflammatory, and anti-apoptotic effects. In the present study, we have examined the effect of CAR treatment on learning-memory impairment in a post-menopausal hypertensive rat model that was induced by ovariectomy following two-kidney, one-clip renovascular hypertension surgery.

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We investigated the effects of an ethanolic extract of subsp. (MC) leaves on the pancreases of rats fed with a high fat diet (HFD). Wistar albino rats were fed either with standard lab chow (Control group) or with a 45% fat diet (HFD and HFD+MC groups) for 4 months, with the MC extract (100 mg/kg) being administered by orogastric gavage to rats in the HFD+MC group during the last month.

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Article Synopsis
  • Nephrolithiasis, a common kidney condition that can lead to kidney failure, is influenced by oxidative stress, prompting research into agents that may alleviate this issue, such as MC extract, known for its antioxidant properties.* -
  • The study involved Wistar albino rats divided into four groups, where nephrolithiasis was induced using ethylene glycol, and the effects of preventive and therapeutic MC extract were evaluated through urine and tissue analysis.* -
  • Results showed that MC extract successfully normalized urine and tissue parameters associated with oxidative stress and tissue damage, indicating potential for clinical use in preventing kidney stone formation through further research.*
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