Recognition of malignant processes with neural nets from ESR spectra of serum albumin.

Cancer diseases are the focus of intense research due to their frequent occurrence. It is known from the literature that serum proteins are changed in the case of malignant processes. Changes of albumin conformation, transport efficiency, and binding characteristics can be determined by electron spin resonance spectroscopy (ESR).

Albumin transport analysis of different collected and processed plasma products by electron spin resonance spectroscopy.

Background: Changes of albumin conformation flexibility and binding characteristics in plasma products can be determined by electron spin resonance spectroscopy (ESR) with spin probes as reporter molecules.

Methods: Quality of albumin transport was analyzed in different processed plasma units using a new ESR method which provides estimation of albumin properties by examination of albumin molecular structure changes.

Results: In serum of healthy donors could not be obtained any abnormalities.

Partner relationships of depressives.

A study of the partnerships of 15 endogenous bipolar, 15 endogenous unipolar, 15 neurotic and 16 unclassified depressives, and of 36 control persons showed that there were some common factors and some differences due to sex among the depressives as a total group. The greater differences were to be found, however, among the depressive subgroups. Bipolars: particularly great desire for closeness and for love and attention, low self-esteem where the partner is concerned, the strongest aggression inhibition.

Childhood experiences of endogenous and neurotic depressives.

The parent-child relationship, the relationship between the parents, and the contact of the child with the outside world was investigated on the basis of retrospective interview data concerning the childhood of endogenous and neurotic depressives and a nonclinical control group. A number of significant links between childhood experiences and the various forms of depression emerges.

Aggression in depressives and psoriatics.

The Questionnaire for Measuring Factors of Aggression (Fragebogen zur Erfassung von Aggressivitätsfaktoren, FAF) was completed by 113 depressive patients, 38 psoriatics, and 32 healthy controls. The controls had the lowest aggression scores, the neurotic depressives the highest. The monopolar endogeneous depressives had extremely high scores for autoaggressions and extremely low ones for outward aggressions, whereas the psoriatics show a contrary tendency: extremely high scores for outward aggressions and very low ones for autoaggressions.