Publications by authors named "G Sciacca"
Background: L-dopa (LD) effects on visually guided saccades (VGS) have been poorly investigated in de novo Parkinson's disease (PD) patients through a standardized acute challenge test.
Objectives: To assess the acute saccadic effects of LD as well as possible different patterns of VGS response to LD in a consistent population of de novo PD.
Methods: VGS were assessed among de novo PD at baseline and 2 h after the administration of LD/carbidopa 250/25 mg.
Article Synopsis
- * The research involved 230 patients, analyzing their EEG recordings to determine a power law exponent (β) that reflects brain connectivity and activity patterns.
- * Results showed that tauopathies had lower β values compared to α-synucleinopathies, suggesting that β could serve as a potential biomarker for distinguishing between these two types of neurodegenerative diseases.
Objective: We monitored cognition in 14 Parkinson's disease (PD) patients during deep brain stimulation (DBS) surgery when the electrode was positioned at the target subthalamic nucleus (STN) (i.e., the STN motor area).
View Article and Find Full Text PDFStudy Objective: The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients undergoing elective cardiopulmonary bypass (CPB) surgery.
Design: Prospective, non-randomized, two-step protocol design.
Setting: Cardiac surgery department of Clinique Pasteur, Toulouse, France.
Parkinson's Disease (PD) body-first subtype is characterized by prodromal autonomic symptoms and REM sleep behavior disorder (RBD), symmetric dopaminergic degeneration, and increased risk of dementia. On the other hand, the PD brain-first subtype has fewer non-motor symptoms and a milder motor phenotype. The temporal relationship between RBD onset and motor symptoms onset may differentiate these two subtypes.
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