Publications by authors named "G Schubert"
Background: 90% of glioblastomas (GBM) relapse within two years of diagnosis. In contrast to the initial setting, there is no standard management for recurrent disease and options include hypofractionated stereotactic re-irradiation (re-mHSRT). The aims of this study were to investigate re-mHSRT practice in Swiss neuro-oncology centres.
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- Spontaneous supratentorial intracerebral hemorrhage is a severe type of stroke with high mortality rates, and there are currently no effective treatments to improve patient outcomes.
- This trial will assess the effects of early minimally invasive endoscopic surgery compared to the best medical treatment, focusing on functional outcomes after 6 months.
- Conducted in Switzerland, this multicenter study aims to fill the gap in large randomized trials, potentially establishing new treatment options for this life-threatening condition.
Delayed cerebral ischemia (DCI) is a severe complication following aneurysmal subarachnoid hemorrhage (aSAH), linked to poor functional outcomes and prolonged intensive care unit (ICU) stays. Timely DCI diagnosis is crucial but remains challenging. Dysregulated blood glucose, commonly observed after aSAH, may impair the constant glucose supply that is vital for brain function, potentially contributing to DCI.
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- This study looked at unruptured intracranial aneurysms (UIAs) to see when treatment might need to change from watching to doing surgery.
- Researchers reviewed cases from 2006 to 2022 and found that only 10 out of 144 patients needed a change in treatment after follow-up.
- The main reasons for the changes were growth of the aneurysm or changes in its shape, but none of the patients had a rupture during the study.
The endovascular approach has emerged as standard therapy for many intracranial aneurysms (IAs) to prevent hemorrhage, yet its long-term durability varies considerably. The aim of this study was to evaluate the safety and effectiveness of an initially deliberate endovascular approach regarding IA hemorrhage rates over a long-term follow-up period. This retrospective single-center study included all consecutive patients with endovascularly treated IAs who presented between January 2008 and December 2020 with a follow-up of at least 12 months.
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