Chronic hand eczema can be incapacitating, and there is little knowledge of the efficacy and safety of long-term treatment with topical corticosteroids. We compared the efficacy and safety of two different schedules for the treatment of chronic hand eczema with a potent topical corticosteroid, mometasone furoate. In a prospective, open, randomized trial, 120 patients with chronic hand eczema were treated daily with mometasone furoate fatty cream until the dermatitis cleared or for a maximum of 9 weeks.
View Article and Find Full Text PDFFollowing a survey among all Danish haemophiliac patients 49 HIV-negative patients with chronic hepatitis C were offered enrollment in a randomized controlled open label study comparing two different maintenance regimens following standard interferon-alpha-2b treatment. Dose modifications and treatment discontinuation were based upon changes in transaminase levels. Forty-seven patients enrolled received 3 MU of alpha interferon thrice weekly (TIW) for 3 months.
View Article and Find Full Text PDFFertil Steril
December 1998
Objective: To assess the risk of borderline ovarian cancer among infertile women treated with fertility drugs.
Design: Case-control study.
Setting: Nationwide data obtained from public registers and postal questionnaires.
For more than 20 yrs it has been debated whether the systemic disease sarcoidosis predisposes to malignant neoplasms. The aim of this study was to examine the occurrence of cancer in Danish sarcoidosis patients observed for 9-30 yrs. The clinical data of 555 consecutive sarcoidosis patients were linked with the nationwide Danish Cancer Registry in a database, comparing the results with the expected incidence in the Danish population, adjusted for sex, age and calendar time.
View Article and Find Full Text PDFWe analysed marital status and survival from colorectal cancer among 9596 patients in a nationwide Danish study with complete follow-up of 22-26 years. After exclusion of 2294 patients with missing information, adjusted survival among married patients diagnosed with colon cancer was significantly longer (RR = 0.85; 95% CI: 0.
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