Minimal influence of the anterolateral knee ligament on anterior and rotational laxity of the knee: a cadaveric study.

Knee laxity may be impacted by rupture of the anterolateral knee ligament (ALL). The goal of this study was to measure tibial translation and rotation as a function of the status of the ALL and the anterior cruciate ligament (ACL). Five pairs of fresh frozen cadaver specimens were analyzed.

Experimental validation of the GNRB for measuring anterior tibial translation.

Introduction: The objective of this study was to validate the technique used to measure anterior tibial translation in cadaver knees using the GNRB device by comparing it with the gold standard, the OrthoPilot navigation system.

Hypothesis: Simultaneous measurement of anterior tibial translation by the GNRB and the OrthoPilot in the chosen experimental conditions will result in significant differences between devices.

Material And Methods: Five fresh frozen cadavers were used.

A randomized clinical trial to compare fleroxacin-rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection.

Background: Oral combination therapy with fluoroquinolones plus rifampicin is a promising alternative to standard parenteral therapy for staphylococcal infections.

Methods: In a multicenter, randomized trial, we compared the efficacy, safety, and length of hospital stay for patients with staphylococcal infections treated either with an oral combination of a fluoroquinolone (fleroxacin) plus rifampicin or with standard parenteral treatment (flucloxacillin or vancomycin). Patients were included if cultures showed the presence of bacteremia or deep-seated infections with Staphylococcus aureus (104 patients) or catheter-related bacteremia due to drug-susceptible, coagulase-negative staphylococci (23 patients).

Detection of human immunodeficiency virus type 1 (HIV-1) RNA in pools of sera negative for antibodies to HIV-1 and HIV-2.

A total of 234 pools were prepared from 10,692 consecutive serum samples negative for antibodies to human immunodeficiency virus type 1 (HIV-1) and HIV-2 collected at five virological laboratories (average pool size, 45 serum samples). Pools were screened for the presence of HIV-1 RNA by a modified commercial assay (Amplicor HIV-1 Monitor test) which included an additional polyethylene glycol (PEG) precipitation step prior to purification of viral RNA (PEG Amplicor assay). The sensitivity of this assay for HIV-1 RNA detection in individual serum samples within pools matches that of standard commercial assays for individual serum samples, i.