Methylglyoxal alters collagen fibril nanostiffness and surface potential.

Collagen fibrils are fundamental to the mechanical strength and function of biological tissues. However, they are susceptible to changes from non-enzymatic glycation, resulting in the formation of advanced glycation end-products (AGEs) that are not reversible. AGEs accumulate with aging and disease and can adversely impact tissue mechanics and cell-ECM interactions.

High-speed telescope autofocus for UAV detection and tracking.

This paper presents the analysis, implementation and experimental evaluation of a high-speed automatic focus module for a telescope-based UAV detection and tracking system. An existing optical drone detection system consisting of two telescopes and deep learning-based object detection is supplemented by suitable linear stages and passive focus algorithms to enable fast automatic focus adjustment. Field tests with the proposed system demonstrate that UAVs flying at speeds of up to 24 m/s towards the system are successfully tracked and kept in focus from more than 4500 m down to 150 m.

Reconstructing highly divergent wavefronts from sparse measurements.

The paper presents a concept for the sparse measurement and reconstruction of highly divergent wavefronts enabling measurements at high throughputs and beyond the dynamic range of the wavefront sensor. In the proposed concept, a direct measurement of the wavefront is carried out, where a few segments of the wavefront are measured with Shack-Hartmann sensors (SHSs). In total about 1% of the wavefront is measured and used for the reconstruction of the entire wavefront, which makes the concept suitable for applications where low measurement times are needed.

Fast modal reconstruction of large plane wavefronts from sparse measurements using Shack-Hartmann sensors.

A concept for the fast measurement and reconstruction of optical wavefronts using Shack-Hartmann sensors (SHSs) is presented. For wavefronts with a diameter at the scale of several tens of millimeters, hundreds of measurements with an SHS may be necessary to cover the wavefront. In the proposed concept, a few SHSs are used to measure about 2% of the entire wavefront, providing sufficient measurement data for its successful reconstruction.

Camera-guided real-time laser ranging for multi-UAV distance measurement.

This paper presents the design and implementation of a scalable laser ranger finder (LRF)-based prototype system, which enables distance measurement and precise localization of multiple unmanned aerial vehicles (UAVs) in real-time. The system consists of a telescope and camera as the image acquisition components, supplemented by an LRF and a fast steering mirror (FSM) to obtain the distance measurement. By combining the optical path of the camera and the LRF through a dichroic mirror, the LRF is accurately aligned by the FSM based on the angular position of a UAV within the camera field of view.