Publications by authors named "G Schinas"
Background: The risk of severe coronavirus disease 2019 (COVID-19) in pregnant women is elevated.
Aim: To examine the outcomes of pregnant women with COVID-19 and report perinatal outcomes and complications, while providing a brief review of current literature.
Methods: The study included pregnant women presenting from April 2020 to February 2022 to the emergency department (ED) of a tertiary hospital.
The COVID-19 pandemic has prompted interest in identifying reliable biomarkers to predict disease severity and guide clinical decisions. Prolactin (PRL), a hormone traditionally associated with lactation, has gained attention for its role in immune modulation. This study aimed to assess PRL as a biomarker for disease severity in COVID-19.
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- - Vulvovaginal candidosis (VVC) is a prevalent condition among women, but existing diagnostic methods are often inefficient and result in delayed treatment due to the need for specialized training and lengthy processes.
- - A review of 23 studies showed that molecular diagnostic tools, particularly NAAT/PCR assays, have high sensitivity and specificity for VVC compared to traditional methods, while simpler DNA probes have lower sensitivity.
- - Despite the advancements in molecular diagnostics, traditional methods still play an important role, especially in settings with limited resources, and emerging technologies like AI show potential to further enhance diagnosis and treatment outcomes.
Article Synopsis
- Vulvovaginal candidosis (VVC) is a common and troublesome vaginal infection, and many patients experience recurrent cases even after antifungal treatment.
- Probiotics may serve as a useful alternative or complementary treatment option for managing VVC, as studies suggest they could improve patient outcomes, even though current findings on their effectiveness are mixed.
- The research indicates that while antifungals like fluconazole are still more effective, combining them with probiotics could help reduce recurrence and improve symptoms, prompting a need for more targeted future studies on probiotics' roles in VVC treatment and prevention.
Bloodstream infections (BSIs) can be primary or secondary, with significant associated morbidity and mortality. Primary bloodstream infections (BSIs) are defined as infections where no clear infection source is identified, while secondary BSIs originate from a localized infection site. This study aims to compare patterns, outcomes, and medical costs between primary and secondary BSIs and identify associated factors.
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