Oxalate in human seminal plasma: possible significance and problems of oxalate determination.

Objective: To determine the level of oxalate in seminal plasma and to correlate it with andrologic variables.

Design: Laboratory examination.

Setting: University-based department of andrology and department of clinical chemistry.

Prostate-specific antigen (PSA) in human seminal plasma.

Prostate-specific antigen (PSA) was measured in seminal plasma and serum of 113 men under investigation for involuntary barrenness. PSA in seminal plasma was 0.4 +/- 0.

Sperm motility index.

Within 40 s the Sperm Quality Analyzer (United Medical Systems, Santa Ana, CA, USA) provides a numerical value called the sperm motility index. This index reflects both the concentration of motile sperm cells and the intensity of their motility and cannot be determined by conventional semen analysis. To assess the diagnostic value and reliability of the sperm motility index, 155 ejaculates were investigated by the sperm quality analyzer and routine manual methods.

Mercury in urine and ejaculate in husbands of barren couples.

Mercury concentrations in morning urine and ejaculate were detected in 80 husbands of women presenting for infertility treatment. Additionally, the number of their dental amalgam fillings was documented. A routine spermiogram was performed, from which a numerical "fertility index" was calculated.

Triprolidine: 104-week feeding study in rats.

The antihistamine triprolidine hydrochloride, was fed at dietary concentrations of 0, 250, 1000, or 2000 ppm (as the free base) to groups of 60 Fischer 344 (F344) rats of each sex for up to 2 years to evaluate its potential carcinogenicity. Up to 12 per sex from each group were killed at 65 weeks, and hematology, clinical chemistry, and histopathology were evaluated. A complete histopathological evaluation was performed on all other animals; survivors were killed at 2 years.