Unlabelled: Parvoviruses are ubiquitous pathogens that cause fatal disease in cats. Feline panleukopenia virus (FPV) is a primitive virus reported first and canine parvovirus (CPV) evolved from FPV and was reported later. Both induce disease in cats and dogs with correlative signs.
View Article and Find Full Text PDFImmune checkpoint blockers have transformed non-small-cell lung cancer treatment, but they can lead to autoimmune and inflammatory side effects, leading to the concurrent use of immunosuppressive treatments. In this analysis, we delve into the potential of antibodies checkpoint blockade, focusing on CTLA-4 inhibition using ipilimumab, as a groundbreaking cancer immunotherapy. We also concentrate on the role of biomarkers, particularly PD-L1 activity and mutation significance, in predicting the response to programmed cell death protein 1 blockage and the prevalence of side effects associated with immune-related side effects.
View Article and Find Full Text PDFis a flowering plant belonging to a genus of the dicotyledonous herbaceous annual flowering plant of the Asteraceae (Compositae) family. It is a perpetual flowering plant, mostly cultivated for medicinal purposes; generally, used in popular drinks due to its aroma and flavor. It is primarily cultivated in China, Japan, Europe, and United States.
View Article and Find Full Text PDFThis present investigation is carried out to study the effect of algal and bacterial inoculum concentrations on the removal of organic pollutants and nutrients from the tannery effluent by the combined symbiotic treatment process. The bacterial and microalgal consortia was developed in laboratory setup and mixed together to perform this study. The Influence of algae and bacteria inoculum concentrations on the removal of pollutants such as Chemical Oxygen Demand (COD) and Total Kjeldahl Nitrogen (TKN) were studied using statistical optimization through Response surface methodology.
View Article and Find Full Text PDFCancer therapy continues to be a huge challenge as most chemotherapeutic agents exert serious adverse effects on healthy organs. Chemotherapeutic agents lack selective targeting and even the existing target specific therapies are failing due to poor distribution into the tumor microenvironment. Nanotechnology offers multiple advantages to address the limitations encountered by conventional therapy.
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