Publications by authors named "G Sarlo"
Article Synopsis
- - Screenings for ADHD and emotional issues are important for children with epilepsy, but there’s not enough research on which screening tools to use in clinics.
- - In a study involving 50 parents of children aged 5-17 with epilepsy, various screening tools were compared, including the Strengths and Difficulties Questionnaire and the Pediatric Quality of Life Inventory.
- - The study found positive screening rates for ADHD (40%-72%) and emotional concerns (38%-46%), with varying levels of agreement between the measures, suggesting that while all are effective, they may differ in specificity and usability.
Article Synopsis
- Current dietary therapies for epilepsy often have side effects and are lacking in nutrients, making the low glutamate diet (LGD) a potentially beneficial alternative that may help reduce seizure activity.
- The study involved a randomized clinical trial of young participants with frequent seizures, assessing the impacts of LGD on seizure frequency and overall health compared to a control group.
- Results showed increased nutrient intake during the LGD intervention, with some clinical improvement noted, but no significant change in seizure frequency; younger participants were more likely to respond positively to the diet.
The objective of this research was to identify caregiver perspectives on dietary therapies for epilepsy, as well as provide future directions for improving caregiver support. A Qualtrics survey was distributed via social media platforms. The survey was aimed towards caregivers with children who are currently using or have previously used dietary therapy for epilepsy.
View Article and Find Full Text PDFAn imbalance between excitation and inhibition has been a longstanding proposed mechanism regarding ictogenesis and epileptogenesis. This imbalance is related to increased extracellular glutamate in the brain and/or reduction in GABA concentrations, leading to excitotoxicity, seizures, and cell death. This review aims to summarize the microdialysis and magnetic resonance spectroscopy (MRS) literature investigating glutamate and GABA concentrations in epilepsy patients, present limitations, and suggest future directions to help direct the search for novel epilepsy treatments.
View Article and Find Full Text PDFObjective: The objectives of this study were to 1) examine medical records from one medium-sized dietary clinic as an example of data being collected clinically, 2) identify data limitations, and then 3) create standardized data collection forms with the long-term goals of improving clinical care and facilitating multicenter data analysis.
Methods: A retrospective chart review was conducted at the Dietary Therapies for Epilepsy Clinic at Children's National Medical Center (CNMC) in Washington, D.C.