Publications by authors named "G Santagostino"
Background: Guidelines indicate that a low-protein diet (LPD) delays dialysis in severe chronic kidney disease (CKD). We assessed the value of these guidelines by performing a retrospective analysis in our renal clinical practice.
Methods: The analysis was performed from 1 January 2010 to 31 March 2018 in 299 CKD Stage 4 patients followed for 70 months in collaboration with a skilled nutritionist.
Purpose: Our purpose is to analyze the outcomes of endovascular aneurysm repair (EVAR) in patients treated with Excluder endograft (W.L. Gore and Associate, Flagstaff, AZ), comparing second generation, featuring SIM-PULL delivery system (ExSP) and third generation, featuring C3 (ExC3), concerning intraprocedural data and long-term outcomes.
View Article and Find Full Text PDFAims: Arrhythmogenic right ventricular (RV) cardiomyopathy (ARVC) is associated with ventricular arrhythmias, even without RV structural disease. We aimed to characterize the RV substrate using electroanatomical mapping and to define outcomes following ventricular tachycardia (VT) ablation in patients with and without RV structural abnormalities.
Methods And Results: Twenty-nine patients with definite or suspected ARVC undergoing VT ablation were classified as 'electrical' and 'structural' cardiomyopathy based on the absence or presence of major structural criteria.
Article Synopsis
- IgA nephropathy (IgAN) shows a wide range of clinical outcomes, with baseline proteinuria being a key risk factor for progression; however, time-average proteinuria (TAp) during follow-up is identified as a stronger indicator of kidney health and treatment response.
- *In a study analyzing 325 IgAN patients from 1989 to 2005, findings reveal that lower TAp correlates with improved renal survival, with a notable 16.6% experiencing significant kidney function decline.
- *Key factors influencing lower TAp and better kidney outcomes include female gender, use of corticosteroids, lower initial protein levels, and blood pressure management, suggesting that a 6-month corticosteroid treatment is effective at improving kidney function
Aims: Patients with non-ischaemic cardiomyopathy (NICM) and ventricular tachycardia can be categorized as anteroseptal (AS) or inferolateral (IL) scar sub-types based on imaging and voltage mapping studies. The aim of this study was to correlate the baseline electrocardiogram (ECG) with endo-epicardial voltage maps created during ablation procedures and identify the ECG characteristics that may help to distinguish the scar as AS or IL.
Methods And Results: We assessed 108 baseline ECGs; 72 patients fulfilled criteria for dilated cardiomyopathy whereas 36 showed minimal structural abnormalities.