Publications by authors named "G Sancini"
We present a case of breast cancer metastases superimposed on epidural lipomatosis and although none of these findings are considered rare, their coexistence leads to unique image findings, and as far as we know there are no other cases like this in literature.
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- The peripheral nervous system can suffer from chemotherapy-induced peripheral neurotoxicity (CIPN) due to common anticancer drugs, leading to long-lasting symptoms like sensory loss and neuropathic pain.
- CIPN significantly impacts the quality of life for cancer survivors, with limited effective treatments currently available.
- The review explores the role of ion channels and transporters in the development of CIPN, aiming to uncover potential new targets for prevention and treatment.
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- The text refers to a correction made to a previously published article, identifiable by its DOI.
- The correction was likely necessary to address errors or inaccuracies found in the original paper.
- The specific details of the correction or the nature of the article are not provided in the text.
Lipid nanoparticles own a remarkable potential in nanomedicine, only partially disclosed. While the clinical use of liposomes and cationic lipid-nucleic acid complexes is well-established, liquid lipid nanoparticles (nanoemulsions), solid lipid nanoparticles, and nanostructured lipid carriers have even greater possibilities. However, they face obstacles in being used in clinics due to a lack of understanding about the molecular mechanisms controlling their drug loading and release, interactions with the biological environment (such as the protein corona), and shelf-life stability.
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- * Diagnosing inner ear issues is complex due to its fragile structure and difficulty in accessing fluid samples, which typically can only be done through surgery, complicating targeted drug delivery.
- * Recent advancements in ultrasharp microneedle technologies promise safer fluid sampling and localized treatment, potentially revolutionizing personalized medicine for inner ear diseases, though more research is needed for clinical application.