This paper presents new experimental and numerical evidence that perforations in a pipe wall result in a low-frequency bandgap within which sound waves rapidly attenuate. These perforations are modelled as an acoustically soft boundary condition on the pipe wall and show that a low frequency bandgap is created from 0 Hz. The upper bound of this bandgap is determined by the dimensions and separation of the perforations.
View Article and Find Full Text PDFIntroduction: Nanoparticle formulation of pitavastatin calcium is a potential alternative to solve the solubility related problem. However, the formulation of nanoparticle involves various parameters that affect product quality. Plackett-Burman design could facilitate an economical experimental plan that focuses on determining the relative significance of many.
View Article and Find Full Text PDFIntroduction: Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood. Several medicinal plants possess curative and protective effect against thrombocytopenia associated with diseases or drugs.
Aim: In the present study, we have investigated the platelet augmentation activity of polyherbal formulation (VITA PLAT Capsule) in cyclophosphamide-induced thrombocytopenic rat model.
Background: Aspartic protease found in plasmodium parasites such as plasmepsin I, II and IV plays an important role in the degradation of hemoglobin. The studies have shown that effective drug must be able to inhibit more than one type of plasmepsin to avoid further growth of parasites and to prevent resistance of drug. Therefore, plasmepsins are believed to be excellent drug target for malarial disease.
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