[The association of megaesophagus, Binder's syndrome and dysautonomia: a new neurocristopathy].

A case of esophageal achalasia is reported in a 12 year-old child. Nasal hypoplasia (Binder syndrome) and dysautonomia were associated. This may be explained by the common embryologic origin (neural crests) of nasal bud, autonomic nervous system and digestive intramural neurons.

[Comparative hepatic toxicity of perhexiline maleate and griseofulvin in mice].

Hepatic toxicity was observed in mice which had received Griseofulvin or Perhexilin Maleate over a period of several months. Treatment of griseofulvin alone gave rise to hepatitis with the presence of Mallory bodies (MB) whereas the same length of treatment with Perhexilin Maleate was associated with steatonecrosis with an absence of MB. When treatment was followed by a one month rest period hepatic lesions disappeared with no trace of sequelae.

[Ultrastructural heterogeneity and assumed mode of formation of Mallory bodies in acute alcoholic hepatitis and in experimental hepatitis].

Mallory bodies (MB) are characteristic features of human and experimental hepatitis they exhibit, by electron microscope, an heterogeneous structure. We propose a mode of formation of such MB, which would take place un a progressive way from simple form (bundles of microfilaments) to complex form (typical MB).