[The dynamics of ischemic heart disease and the risk factors among the male population of Moscow in the 1985 to 1995 period].

The trends in prevalence of ischemic heart disease (IHD) and risk factors for 1985-1995 have been studied on random representative samples of male population from Moscow. For the decade studied IHD incidence increased, especially in younger males. Changes in IHD risk factors were the following: systolic and diastolic pressures were on the increase.

[The characteristics of the levels of the blood pressure, physical development and risk factors for atherosclerosis in schoolchildren living in areas of radioactive contamination].

One-stage epidemiological survey for prevalence of standard risk factors (blood pressure, body weight, atherosclerosis, smoking) has been performed on a representative sample of 828 schoolchildren aged 7-17 living in the Bryansk region (winter 1993). This territory underwent radionuclide contamination after the Chernobyl accident (1-5 Ci/km2). The comparison population consisted of matched schoolchildren from Moscow.

[The epidemiology of systolic and diastolic arterial hypertension in relation to risk factors and education among the male population of some cities of Russia, the CIS nations and the Baltic states (a cooperative study)].

The prevalence of systolic and diastolic arterial hypertension (AH) was studied on a material of random representative samples of male population aged 20-54 years in the cities of Moscow, Saint Petersburg [correction of Sankt-Peterburg], Tallinn, Kiev, Novosibirsk, Alma-Ata, Tashkent and Bishkek. AH was estimated in connection with risk factors (RF) from the standpoint of uni- and multidimensional statistical analysis. It has been established that RF (age, cholesterol and triglycerides concentration, overweight and alcohol use) make more significant contribution into the prevalence of diastolic AH whereas the systolic AH prevalence is largely determined only by age and education.

[A genetic-epidemiological model of predisposition to ischemic heart disease (1)].

A genetic and epidemiological sample of 20-59-year-old males, Moscow residents (n = 3141), was surveyed. The authors obtained data on the prevalence of coronary heart disease from epidemiological criteria and genealogical data on cardiovascular diseases by the "Familial History" questionnaire in the first-degree relatives who were interviewed by using a genetic and mathematical monolocus diallelic model. It was found that out of the 10 possible variants under study a genetic and environmental variant with independent penetrance of 3 genotypes adequately describes the prevalence of coronary heart disease in the families and in the population.