Publications by authors named "G S Rajahram"

The Apicomplexa are a phylum of single-celled eukaryotes that can infect humans and include the mosquito-borne parasite , the cause of malaria. Viruses that infect non- spp. disease-causing protozoa affect the pathogen life cycle and disease outcomes.

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Zoonotic malaria presents a major public health challenge in Southeast Asia. Plasmodium cynomolgi coinfects the same macaque hosts and mosquito vectors as the most common cause of zoonotic malaria, Plasmodium knowlesi. Plasmodium cynomolgi appears morphologically similar to Plasmodium vivax on microscopy and can amplify P.

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Article Synopsis
  • Cases of H5 highly pathogenic avian influenza are increasing, with a high mortality rate of 60% in humans, although no human infections have been reported in Malaysian Borneo despite circulation in local poultry and migratory birds.
  • Deforestation in coastal areas may bring humans closer to these migratory birds, raising the risk of zoonotic spillover events, where diseases jump from animals to humans.
  • A recent survey of over 10,000 individuals found evidence of exposure to H5 viruses, indicating potential human contact with the virus, and emphasizes the need for enhanced surveillance of cross-species pathogen transmission in areas where humans and migratory birds interact.
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Reduced deformability of both infected and uninfected red blood cells (RBC) contributes to pathogenesis in falciparum malaria. Whole blood RBC-deformability is not well-characterised in vivax malaria. We used a laser-assisted optical rotational cell analyzer to measure the RBC deformability in fresh whole blood from Malaysian patients with vivax malaria (n=25).

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Apicomplexa are single-celled eukaryotes that can infect humans and include the mosquito-borne parasite , the cause of malaria. Increasing rates of drug resistance in human-only species are reducing the efficacy of control efforts and antimalarial treatments. There are also rising cases of , the only zoonotic species that causes severe disease and death in humans.

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