Synthesis and Structure-Activity Relationship of Thiourea Derivatives Against .

Leishmaniasis, caused by protozoa and transmitted by vectors, presents varied clinical manifestations based on parasite species and host immunity. The lack of effective vaccines or treatments has prompted research into new therapies, including thiourea derivatives, which have demonstrated antiprotozoal activities. We synthesized two series of ,'-disubstituted thiourea derivatives through the reaction of isothiocyanates with amines.

Physiological and growth responses of tambaqui (Colossoma macropomum) fed Croton conduplicatus essential oil and challenged with Aeromonas hydrophila.

This study aimed to assess the effect of Croton conduplicatus essential oil (CCEO) in diets for tambaqui (Colossoma macropomum) (14.50 ± 0.07 g), a native Amazonian fish.

Extreme Heat Stress and Unplanned Hospital Admissions.

Objectives: The burden and health impact of heat stress on child hospitalization is limited. This study aims to investigate associations between extreme heat stress exposure based on a Universal Thermal Climate Index (UTCI), emergency department (ED) visits, and ED visits that translate into unplanned hospital admissions.

Methods: This population-based case-crossover study included all ED visits and unplanned hospital admissions among children and adolescents aged 0 to 18 years from New South Wales, Australia, from July 2001 to June 2020.

DNA Imprinting and Differentially Expressed Genes in Muscle of Submitted to Early Weaning Management.

Early weaning management followed by energy supplementation can lead to metabolic alterations in the calf that exert long-term effects on the animal's health and performance. It is believed that the main molecular basis underlying these metabolic adaptations are epigenetic mechanisms that regulate, activate, or silence genes at different stages of development and/or in response to different environmental stimuli. However, little is known about postnatal metabolic programming in .

Effect of hay type and breed on the fattening, centesimal and fatty acid composition of Nigerian sheep.

This study aimed to evaluate the intake, performance, quality, and fatty acids (FA) composition of the meat of three Nigerian sheep breeds (Balami, Uda, and Yankasa) fed two different hays, Brachiaria decumbens or Digitaria smutsii. A total of sixty sheep, twenty from each breed, Balami, Uda, and Yankasa, were used, with average body weights of 24.7 ± 3.