[Generalized aspergillosis sepsis in a one month old infant with inborn leukemia].

A rare case of aspergillesis sepsis in an one month old baby with inborn leukemia is reported. Of essential importance in the pathology is genetic deficiency of this child, decreased immunity and a grave intoxication due to leukemia chemotherapy.

[The results of micromorphological and histochemical studies of the musculocutaneous sac of nematodes in the suborder Oxyurata after anthelmintic exposure].

The paper presents the results of studies of the effects of anthelminthic agents on the in tegumentary tissues of nematodes from the Oxyurata suborder. All used anthelmintics causes varying structural changes in the integumentary tissues of Oxyurata. At the same time, there is swelling and loosening of the cuticle, its detachment from the subcuticular layer, vacuolization of the hypodermis and the plasma part of muscular cells, as well as irreversible changes in the cellular organoids of the hypodermis and muscular cells (destruction of canals of the endoplasmic network and the Golgi apparatus, mitochondrial membrane damage, nuclear pyknosis or lysis etc.

[The structure and anthelmintic action of tricyclic analogs of praziquantel and 4-acylpiperazinones-2].

The toxicity and anthelminthic activity of the earlier synthetized tricyclic analogues of praziquantel and 4-acylpiperazinones-2 have been studied. Tricyclic compounds have shown the acute toxicity similar to that of praziquantel and neurotoxic effect typical of praziquantel. 4-acylpiperazinones-2 toxicity correlated with their anthelminthic effect.