Publications by authors named "G S Jacobson"

Article Synopsis
  • Traumatic brain injury (TBI) is a significant cause of mortality and disability in the U.S., and the peripheral vestibular system may be particularly at risk for damage in those with TBI.
  • A study utilized cervical and ocular vestibular evoked myogenic potentials (VEMPs) and video head impulse tests (vHIT) to assess vestibular function and quality of life among individuals with chronic moderate-severe TBI compared to non-injured participants.
  • Results indicated that a high percentage (63%) of TBI patients exhibited abnormal VEMP responses and reported vestibular symptoms, with many indicating these symptoms adversely affected their quality of life, underscoring the importance of vestibular testing for effective rehabilitation.
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Skeletal muscle mass plays a pivotal role in metabolic function, but conditions such as bed rest or injury often render resistance training impractical. The beta-adrenergic receptor has been highlighted as a potential target to promote muscle hypertrophy and treat atrophic conditions. Here, we investigate the proteomic changes associated with beta-adrenergic-mediated muscle hypertrophy, using resistance training as a hypertrophic comparator.

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Using high-resolution 3D printing, a novel class of microneedle array patches (MAPs) is introduced, called latticed MAPs (L-MAPs). Unlike most MAPs which are composed of either solid structures or hollow needles, L-MAPs incorporate tapered struts that form hollow cells capable of trapping liquid droplets. The lattice structures can also be coated with traditional viscous coating formulations, enabling both liquid- and solid-state cargo delivery, on a single patch.

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