Quercetin protected the gut barrier in ulcerative colitis by activating aryl hydrocarbon receptor.

Background: Ulcerative colitis (UC) is characterized by abdominal pain and bloody diarrhoea and restoring the gut barrier is the core goal of UC treatment. Activation of aryl hydrocarbon receptor (Ahr) was reported to effectively alleviate symptoms and repair the gut barrier damage. Neutrophil extracellular traps (NETs) have been recognized as potential targets in the treatment of UC.

Scale-Adaptive viable tumor burden estimation via histopathological microscopy image segmentation.

Cancer segmentation in whole-slide images is a fundamental step for estimating tumor burden, which is crucial for cancer assessment. However, challenges such as vague boundaries and small regions dissociated from viable tumor areas make it a complex task. Considering the usefulness of multi-scale features in various vision-related tasks, we present a structure-aware, scale-adaptive feature selection method for efficient and accurate cancer segmentation.

Constructing Z-scheme between graphite nitride carbon and supramolecular zinc porphyrin to promote photocatalytic H evolution.

The separation and transport of charge carriers between heterojunction interfaces are key factors that constrain their photocatalytic activity. In current study, a new binary heterojunction (BCN-N-SA) composed of g-CN nanosheet (BCN-N) and self-assembled supramolecular zinc porphyrin (SA-ZnTCPP) was successfully synthesized for photocatalytic hydrogen evolution (PHE) from water splitting. The optimal PHE rate of BCN-N-SA reaches 23.

A study of the effect of question feedback types on learning engagement in panoramic videos.

Introduction: The immersive and interactive nature of panoramic video empowers learners with experiences that are infinitely close to the real environment and increases the use of imagination in learners' knowledge acquisition. Studies have shown that embedding question feedback in traditional educational videos can effectively improve learning. However, little research has been conducted on embedding question feedback in panoramic videos to explore what types of question feedback effectively improve the dimensions of learners' learning engagement and yield better learning experiences and learning effects.

Identification of the LCOR-PLCL1 pathway that restrains lipid accumulation and tumor progression in clear cell renal cell carcinoma.

Clear cell renal cell carcinoma (ccRCC) is the typical pathological subtype of renal cell carcinoma (RCC), representing about 80% of RCC. Reprogramming of lipid metabolism is one of the nonnegligible pathogeneses in ccRCC. Currently, the underlying regulatory mechanisms of lipid metabolism in ccRCC remain inadequately understood.