Publications by authors named "G S Gopal"

The pervasive application of pharmaceuticals in aquatic environments has acquired much focus owing to their nonbiodegradability and eco-toxicity, which might readily destroy the ecological balance. Developed chitosan-coated Fe-Cu CNS alginate-CMC beads (NBs) were utilized in this study to adsorb the quinolone antibiotic norfloxacin (NOR) from water for the first time. Under ideal conditions (: 20 mg L; sorbent conc.

View Article and Find Full Text PDF

Background: Limited data exists regarding risk factors for adverse outcomes in older adults hospitalized with Community-Acquired Pneumonia (CAP) in low- and middle-income countries such as India. This multisite study aimed to assess outcomes and associated risk factors among adults aged ≥60 years hospitalized with pneumonia.

Methods: Between December 2018 and March 2020, we enrolled ≥60-year-old adults admitted within 48 hours for CAP treatment across 16 public and private facilities in four sites.

View Article and Find Full Text PDF
Article Synopsis
  • * The Indian polyvalent antivenom is designed to combat the venom from the most dangerous snakes—such as the Spectacled cobra and Russell's viper—but many other species also contribute to severe envenomations.
  • * A systematic review and meta-analysis were performed to assess the neutralization efficiency of the antivenom against snake venoms, revealing significant variability in its effectiveness and highlighting factors affecting recognition of venom toxins.
View Article and Find Full Text PDF
Article Synopsis
  • The study estimates the economic impact of acute respiratory illnesses (ARIs) on adults aged 60 and older in India, focusing on costs associated with medical care and effective preventive measures like vaccines.
  • A total of 6016 participants were monitored over 1.5 years, revealing that pneumonia cases incurred higher costs, with a significant portion being indirect costs due to lost productivity.
  • The findings suggest urgent public health interventions are needed to reduce the burden of ARIs, particularly among vulnerable older adults, as annual costs average around $29.5 per person.
View Article and Find Full Text PDF

Background: We present post-vaccination nasal shedding findings from the phase IV, community-based, triple-blinded RCT conducted to assess efficacy of trivalent LAIV and inactivated influenza vaccines in rural north India.

Methods: Children aged 2-10 years received LAIV or intranasal placebo across 2015 and 2016, as per initial allocation. On days 2 and 4 post-vaccination, trained study nurses collected nasal swabs from randomly selected subset of trial participants based on operational feasibility, accounting for 10.

View Article and Find Full Text PDF