[Clinical significance of "night acid burst" phenomenon in patients with duodenal ulcer].

The article discloses the results of the examination and treatment of duodenal ulcer patients with or without "nocturnal gastric acid breakthrough". This phenomenon was recorded in 19% patients. They have night heartburn, complicated duodenal ulcer in anamnesis, on the one hand, and more long duration of ulcer healing, decreasing efficiency of eradication Helicobacter pylori, on the other hand.

[Circadian rhythms of acid production and alkalization in the stomach of healthy subjects and duodenal ulcer patients].

We studied 24-h rhythms of acid production and alkalization in 30 patients with duodenal ulcer (DU) and 30 healthy subjects using upper endoscopic examination and computer intragastric pH-metry. Gastric acid production was higher in DU patients and was more intensive in the daytime than at night. Healthy subjects had low and monotonous acid production.

[Characteristics of the psychological status of patients with peptic ulcer].

The article discusses changes in the psychological status and the forming of various types of attitude towards the disease in patients with a favorable and unfavorable course of peptic ulcer (PU). The subjects of the study were 82 patients with exacerbation of PU; among them there were 30 patients with a favorable and 52 patient with a complicated course. Patients with a favorable course of PU did not displayed prominent peaks in SMOL profile, which reflected a relatively benign state of their psychological status.

[On correlations between the clinical course of peptic ulcer and the patients, compliance and quality of life].

The article is dedicated to changes in life quality (LQ) and mental status, and to forming of various types of response to the disease in patients with benign and unfavorable course of peptic ulcer (PU). The subjects were 140 patients in acute phase of PU, in 66 of whom the course of the disease was benign, and in 74--unfavorable. In both groups there were patients with low and satisfactory LQ.

[Quality of life and vegetative status of patients with ulcer disease].

Aim: To analyse features of vegetative status of patients with ulcer disease (UD) with reference to quality of life (QL), course of UD, clinical and secretory-motor characteristics.

Material And Methods: A total of 200 UD patients were examined. UD was at the stage of exacerbation, new-onset, with a favourable or unfavourable course.