Publications by authors named "G Rubio Linares"
Article Synopsis
- An efficient enzymatic method was used to create new retinoic acid derivatives, yielding nine compounds, four of which were previously unreported.
- The optimal reaction conditions were explored by testing different variables like enzyme source, solvent, and temperature, enhancing the overall efficiency of the process.
- Some of the new compounds showed lower toxicity than retinoic acid and significantly higher antiviral activity against HSV-1 and HSV-2.
Article Synopsis
- A study evaluated the safety and efficacy of endovascular thrombectomy in patients with acute large-vessel occlusion and tandem lesions, focusing on those with low (0-5) and high (6-10) Alberta Stroke Program Early Computed Tomography Scores (ASPECTS).
- The analysis included 691 patients, revealing that those with low ASPECTS had significantly lower odds of achieving a favorable functional outcome (mRS 0-2) and higher odds of suffering symptomatic intracranial hemorrhage compared to those with high ASPECTS.
- The researchers concluded that endovascular thrombectomy may lead to poorer functional recovery in patients with tandem lesions and low ASPECTS, particularly in the
Article Synopsis
- Botulism is a serious disease caused by a toxin from Clostridium botulinum, leading to muscle paralysis and respiratory issues; diagnosing it can be tough without typical risk factors, such as honey consumption.
- A documented case of infant botulism in Sicily involved an exclusively breastfed baby showing symptoms like poor suction and hypotonia, without any obvious food contamination history.
- The key to the successful treatment was recognizing the signs early, administering botulinum antitoxin, and confirming the diagnosis through tests, emphasizing the need for awareness of all possible exposure sources, including inhalation of contaminated dust.
Purpose: Contrast enhancement (CE) after mechanical thrombectomy (MT) remains a subject of investigation, with a reported prevalence ranging from 31 to 88%. We examined our patients to identify predictors of CE and its impact on outcomes, an aspect that remains understudied.
Methods: We retrospectively analyzed 106 patients who underwent MT at our hospital between 2018 and 2022.
Article Synopsis
- Cervical artery dissection (CeAD) is a leading cause of ischemic strokes in young adults, and this study explored the effects of intravenous thrombolysis (IVT) on patients with CeAD and stroke symptoms.
- Analyzed data from the STOP-CAD study, it found that IVT significantly improved functional independence after 90 days in patients without increasing the risk of symptomatic intracranial hemorrhage.
- The results suggest that IVT is a beneficial treatment for eligible patients with CeAD, aligning with current medical guidelines on its use.