- Acute liver failure is a serious condition affecting about 2,000-3,000 people yearly in North America, characterized by liver injury, hepatic encephalopathy, and coagulopathy, usually occurring in individuals without a prior liver disease history.
- Major causes include paracetamol poisoning, viral hepatitis, and drug-induced liver damage, making it essential to identify the specific cause for effective treatment and better prognosis.
- While survival rates have improved through supportive therapy and medications like N-acetylcysteine, liver transplantation remains a key option for severe cases, with success dependent on timely evaluation and individual patient factors.