Publications by authors named "G Rosafio"
Vitamin D plays a pivotal role in calcium and phosphorus metabolism, also influencing bone tissue. Several studies have reported that vitamin D blood levels were significantly lower in people with obesity, probably due to its uptake by the adipose tissue. Clinical studies that investigated the changes of circulating levels of vitamin D following weight loss reported controversial data.
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- Cholesterol plays a crucial role in the body, but high levels, particularly low-density lipoprotein cholesterol (LDL-C), increase the risk of cardiovascular issues, leading to research on dietary impacts, especially from dairy products.
- A study involving 802 healthy adults in Palermo, Sicily, aimed to examine the relationship between LDL-C levels, dairy consumption, and body metrics, using validated questionnaires and measurements.
- The results indicated that while other factors like age, BMI, and blood pressure correlated with higher LDL-C levels, there was no significant link between LDL-C levels and overall dairy intake, though milk intake was higher in the low LDL-C group.
Endothelial Function in Obese Patients Treated with Bariatric Surgery.
Diabetes Metab Syndr Obes
February 2020
Article Synopsis
- Bariatric surgery (BS) is increasingly used to treat morbid obesity and can lower total mortality and cardiovascular risks, but its effects on endothelial function are unclear.
- This study involved 17 obese patients who underwent BS and 18 who received medical nutrition treatment (MNT), comparing their endothelial function and atherosclerosis markers through measurements like flow-mediated dilation (FMD) and carotid intima-media thickness (c-IMT).
- Results showed significant weight loss in the BS group but a decline in endothelial function was observed after BS, suggesting that BS might contribute to atherosclerosis, while MNT did not significantly impact endothelial function.
Irisin is a recently discovered exercise-induced myokine that has been attributed the role of favoring white-to-brown adipose tissue trans-differentiation. We confirmed in a population-based cohort that irisin serum concentrations are independently correlated with the habitual level of physical activity, but we also observed an independent correlation with serum concentrations of high-sensitivity C-reactive protein (hs-CRP), thus suggesting that inflammation may influence irisin production. In order to investigate the association between irisin and inflammation, we measured serum irisin concentrations in a group of inflamed inpatients.
View Article and Find Full Text PDFDifferent studies have indicated that thiazide diuretics can increase the risk of developing type 2 diabetes (T2D). Therefore, in this study, we investigated whether switching from hydrochlorothiazide (HCTZ) to amlodipine resulted in ameliorating different cardiovascular and metabolic measures in hypertensive patients with or without T2D. This study [Diuretics and Diabetes Control (DiaDiC)] was a 6-week, single-blind, single-center randomized controlled trial.
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