Publications by authors named "G Roks"

Background And Objectives: The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). Possibly, the lack of a beneficial effect in all patients with aSAH is masked by antagonistic effects of TXA in certain subgroups. In this post hoc subgroup analysis, we investigated the effect of TXA on clinical outcome in patients with good-grade and poor-grade aSAH.

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Objective: We investigated motivations of patients and care partners for their memory clinic visit, and whether these are expressed in consultations.

Methods: We included data from 115 patients (age 71 ± 11, 49% Female) and their care partners (N = 93), who completed questionnaires after their first consultation with a clinician. Audio-recordings of these consultations were available from 105 patients.

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Background And Objectives: The ULTRA trial showed that ultra-early and short-term tranexamic acid treatment after subarachnoid hemorrhage did not improve clinical outcome at 6 months. An expected proportion of the included patients experienced nonaneurysmal subarachnoid hemorrhage. In this post hoc study, we will investigate whether ultra-early and short-term tranexamic acid treatment in patients with aneurysmal subarachnoid hemorrhage improves clinical outcome at 6 months.

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Objective: To investigate the influence of frailty in elderly with severe TBI on mortality and functional outcome.

Method: 126 patients with TBI aged 60 years or older and with a presenting Glasgow Coma Scale score of 8 or lower were retrospectively included. To investigate frailty, we used the CSHA Clinical Frailty Scale.

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Article Synopsis
  • Aneurysmal subarachnoid hemorrhage (aSAH) is a serious condition that necessitates intensive care, and the study aimed to evaluate whether levels of C-terminal proarginine vasopressin (CT-proAVP) can predict poor outcomes, mortality, and delayed cerebral ischemia (DCI) in patients compared to existing scoring systems.
  • The research examined CT-proAVP levels in 100 patients with aSAH and found that higher levels of CT-proAVP were significantly correlated with worse functional outcomes at one year, as well as with mortality within 30 days and one year.
  • Though CT-proAVP showed high accuracy for predicting poor outcomes and mortality (with AUC values around 0.84
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