Publications by authors named "G Roider"

Article Synopsis
  • Some medications can increase the QT interval, which can be life-threatening, especially when combined with other risk factors.
  • In a study of 3040 forensic autopsy cases over five years, 6% showed at least one drug that could prolong the QT interval among individuals with undetermined causes of death.
  • Key risk factors linked to fatal heart issues included a history of drug or alcohol abuse, heart problems, and the use of multiple QT-prolonging medications, with antipsychotics being the most commonly found among these cases.
View Article and Find Full Text PDF
Article Synopsis
  • Elderly individuals with comorbidities are at higher risk for kidney disease and drug interactions due to the use of multiple medications (polypharmacy).* -
  • A study analyzed 3,040 post-mortem cases, finding that 3.8% had a history of renal failure, highlighting the importance of monitoring kidney function in these patients.* -
  • Thirteen deaths were linked to improper drug dosing, with nearly half caused by lactic acidosis from metformin accumulation, suggesting that correct dose adjustments could prevent serious drug toxicity.*
View Article and Find Full Text PDF

Synthetic cannabinoid receptor agonists (SCRAs, "Spice") are a diverse group of recreational drugs, with their structural and pharmacological variability still evolving. Forensic toxicologists often rely on previous reports to assess their role in intoxication cases. This work provides detailed information on the "Spice"-related fatalities around Munich, Germany, from 2014 to 2020.

View Article and Find Full Text PDF

Purpose: In forensics, entomological specimens can be used as additional/alternative matrices to detect xenobiotics when human specimens are limited in their application. Despite some advantages over implementing putrefied human remains, most medico-legal laboratories do not include entomotoxicological procedures as routine analytical methods. We thus applied two authentic cases to evaluate necrophagous larvae's potential as complementary matrices for toxicological analysis after extensive postmortem decomposition.

View Article and Find Full Text PDF

In Kadoma (Zimbabwe) gold is extracted from ore based on a simple technology using mercury. Women are exposed whilst living in an exposed area, or even more working directly with mercury. Breast fed infants are exposed via mercury contaminated milk and the general environmental mercury exposure.

View Article and Find Full Text PDF