Publications by authors named "G Roederer"

Background: Automated office blood pressure (AOBP) measuring devices are increasingly recommended as preferred blood pressure (BP) diagnostic tools, but it is unclear how they compare and how clinical environments impact their performance.

Methods: This prospective randomized factorial parallel 4-group study compared BP estimates by BpTRU (VSM MedTech, Vancouver, BC, Canada) and Omron HEM 907 (Omron Healthcare, Kyoto, Japan) devices in closed vs open areas. Patients diagnosed with hypertension were recruited during office visits.

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Background: Blood pressure (BP) readings taken in clinics are often higher than BP readings taken in a research setting. Recent guidelines and clinical trials have highlighted the necessity of using automated office blood pressure (AOBP) devices and standardizing measurement procedures. The goal of the present study was to compare AOBP vs manual BP measurement in both research and clinical environments in which operators and devices were the same and measurement procedures were standardized and optimal.

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Statins are effective drugs to reduce cardiovascular events secondary to dyslipidemia; however, they cause frequent undesirable side effects. The incidence of statin-induced myotoxicity (SIM) is presented by 7 to 29% of patients, depending upon the report. SIM may develop in presence of abnormally high concentrations of statins in the myocyte and/or in presence of muscular conditions that may predispose to SIM.

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Objective: Locking plates have become a standard implant in the treatment of distal femoral fractures. Newer designs allow polyaxial screw placement as well as the ability to lock the lag screws.

Methods: The consecutive multi-centre study cohort consists of all distal femoral fractures treated with the NCB® Distal Femur plate (Zimmer, Warsaw, USA) and a minimum follow-up of twelve months.

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Article Synopsis
  • Ursodeoxycholic acid (UDCA) is a bile acid used for treating gallstones and cholestatic liver diseases, but this study aimed to see if it could also lower cholesterol in patients with hypercholesterolemia without liver issues.
  • A multicenter randomized, double-blind, placebo-controlled trial involved 134 eligible patients, who were assigned to either UDCA or placebo for 24 weeks after a 6-week placebo lead-in.
  • Results indicated that UDCA did not significantly lower LDL cholesterol or other lipid levels compared to placebo, confirming it is not effective for type IIa or IIb hypercholesterolemia, though it was found to be safe and well tolerated.
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