Publications by authors named "G Riario Sforza"

Article Synopsis
  • The study investigates coping strategies in adolescents with primary migraines, focusing on their responses to stress and how these relate to migraine characteristics like frequency and intensity.
  • It highlights that school and socialization are common stressors, with high-frequency headache patients using less effective coping methods, leading to increased anxiety and depression.
  • The findings suggest a connection between the maladaptive coping strategies and psychological symptoms, indicating the need for tailored interventions for young migraine sufferers.
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Article Synopsis
  • * The study involved a literature review of existing research on the use of mTOR inhibitors for managing TSC during pregnancy, focusing on case reports and studies of pregnant women and prenatal mouse models.
  • * Preliminary findings suggest that mTOR inhibitors could effectively reduce cardiac rhabdomyomas, but more research is necessary to understand their potential in preventing neurological issues while ensuring safety for fetal development.
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Article Synopsis
  • * A total of 98 patients with migraine and 98 healthy controls were analyzed for gut microbiota diversity and metabolic pathways in fecal samples, finding significant differences between the two groups.
  • * Results indicated that migraine patients had greater bacterial richness and specific metabolic changes, along with markers of gut inflammation and increased intestinal permeability, highlighting the distinct GM profiles in pediatric migraine cases.
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Background: Chronic migraine (CM) negatively impacts the quality of life of 2 to 4% of pediatric patients. In adults, CM is frequently linked to medication overuse headache (MOH), but there is a much lower prevalence of MOH in children. A suboptimal response to acute therapies may lead to their reduced use, thus preventing MOH development in children and adolescents.

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Despite its rarity, cluster headache can affect children. Patients with cluster headaches often experience symptoms in their adolescence, but the time it takes for a correct diagnosis can be very long. Cluster headache can be mistaken for other pathologies, which can result in patients being diagnosed and treated incorrectly.

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