Publications by authors named "G Renga"

Celiac disease (CD) is an autoimmune enteropathy resulting from an interaction between diet, genome, and immunity. Although many patients respond to a gluten-free diet, in a substantive number of individuals, the intestinal injury persists. Thus, other factors might amplify the ongoing inflammation.

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Article Synopsis
  • Multiple sclerosis is a serious disease where the immune system attacks the central nervous system, causing inflammation.
  • Scientists found that a substance made by gut bacteria, called indole-3-carboxaldehyde (3-IAld), seems to help with this disease by affecting how the body uses a chemical called tryptophan.
  • This process could protect the body and might even lead to new treatments for autoimmune diseases like multiple sclerosis.
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Background: The recent Coronavirus Disease 2019 (COVID-19) pandemic has dramatically exposed our gap in understanding the pathogenesis of airborne infections. Within such a context, it is increasingly clear that the nasal cavity represents a critical checkpoint not only in the initial colonization phase but also in shaping any infectious . This is particularly relevant to COVID-19 in that the nasal cavity is characterized by high-level expression of the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) receptor, Angiotensin-Converting Enzyme 2 (ACE2), all along the respiratory tract.

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Article Synopsis
  • CPX-351 is a special medicine approved for adults with a type of leukemia called acute myeloid leukemia (AML) that helps them live longer and do better after getting a stem cell transplant.
  • It protects the gut (our digestive system) from getting damaged during treatment, unlike another treatment called "7 + 3."
  • The study showed that CPX-351 works well because it helps our body's defenses and changes the gut bacteria in a positive way, which might help doctors treat AML more effectively in the future.
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