Publications by authors named "G Ravi Sundar"
Early versus delayed timing of vitrectomy after open-globe injury.
Cochrane Database Syst Rev
November 2024
Article Synopsis
- This protocol outlines a Cochrane Review focused on the timing of vitrectomy following open-globe injuries.
- The main goal is to compare the effects of performing the surgery early versus later on patients' visual outcomes.
- The review aims to provide evidence that could guide clinical decisions regarding the optimal timing for vitrectomy in such cases.
Article Synopsis
- The study investigates how Butea monosperma bark extract influences the bone-forming ability of rat adipose-derived mesenchymal stem cells (rADMSCs) and its connection to the Wnt/β-catenin signaling pathway.
- Characterization techniques identified bioactive compounds in the extract, and in vitro tests assessed the extract's effects on cell growth, differentiation, and gene expression related to bone formation.
- Results showed that the extract promotes osteogenic differentiation in rADMSCs by activating the Wnt/β-catenin pathway, suggesting its potential as a therapeutic option for improving bone regeneration.
Purpose: When severe retinal and corneal injury occur together, a temporary keratoprosthesis (TKP) is often a last resort to allow posterior segment visualization to enable vitreoretinal surgery, followed by a penetrating keratoplasty (PKP) which can restore corneal clarity in a single operation. We aimed to assess visual outcomes following combined PKP and vitreoretinal surgery with the use of a TKP for cases of ocular trauma.
Design: A systematic literature review was performed following PRISMA guidelines (PROSPERO registration number: CRD42023423518).
Introduction: This article explores the potential challenges in implementing a national-level standardized curriculum for physician associate (PA) programs in India, an initiative under the directions of the National Commission for Allied and Healthcare Professionals Act of 2021.
Methods: Initiated in August 2023, a multistage process began with emailing a draft curriculum for review to key stakeholders, followed by a virtual meeting on September 3. Key stakeholders, including faculty from various universities, participated in focus group discussions (FGDs) at the International Association of Physician Associate Educators and the Indian Association of Physician Assistants annual conference on September 21, 2023, in Gandhinagar.
Article Synopsis
- * Timely surgical intervention is crucial to reduce the risk of serious complications like endophthalmitis, which can affect visual outcomes.
- * A review of 15 studies showed that repairs done within 24 hours significantly lowered the odds of endophthalmitis, but visual outcomes were similar regardless of repair timing.