Publications by authors named "G Rauber"
Article Synopsis
- HDLC is a solid lubricant with superlubricity potential for industrial use, but it shows different friction behavior at nanoscale compared to macroscale tests.
- To achieve superlubricity, HDLC needs to remove a thin air-oxidized layer and transform amorphous carbon into a stable graphitic structure under shear stress.
- The study finds that while transformation to graphitic films occurs, these films are not retained in the nanoscale contact area, which is essential for maintaining superlubricity in HDLC.
Monoglycerides (MGs) such as glycerol monolaurate (GML) and glycerol monostearate (GMS) have been used as excipients in oral formulations because of their emulsifying effect as well as their ability to inhibit the precipitation and intestinal efflux of drugs. Excipient-drug compatibility studies, however, have been underexplored. In this study, benznidazole (BNZ) was selected as a drug model due to the difficulty in improving its solubility and because of the potential impact on public health (it is the only drug currently used to treat Chagas disease).
View Article and Find Full Text PDFThis manuscript reports a three-year follow-up of a case of gingival conditioning with a provisional composite veneer prior to diastema closure and tooth recontouring with direct composites. This conservative treatment resulted in a natural and harmonious smile.
View Article and Find Full Text PDFNanotechnology has been widely used to improve stability, efficacy, release control and biopharmaceutical aspects of natural and synthetic cannabinoids. In this review, the main types of cannabinoid-based nanoparticles (NPs) reported so far are addressed, taking into account the advantages and disadvantages of each system. Formulation, preclinical and clinical studies performed with colloidal carriers were individually analyzed.
View Article and Find Full Text PDFPurpose: To understand the anomalous behavior of Saquinavir Mesylate (SQVM) in sodium decyl sulfate (SDS) medium during a dissolution test through a crystallographic analysis of the crystal obtained. As a result, it will be possible to elucidate its crystal structure and carry out a complete solid-state characterization of the API.
Methods: The solid form obtained was characterized by a structural analysis through X-ray single crystal and powder diffraction.