Publications by authors named "G Rangel"
Background: Artemisia spp. have been used for millennia in traditional medicine to treat a variety of ailments, including malaria. Extracts of Artemisia afra and A.
View Article and Find Full Text PDFUnlabelled: The mitochondrion of the deadliest human malaria parasite, is an essential source of cellular acetyl-CoA during the asexual blood-stage of the parasite life cycle. Blocking mitochondrial acetyl-CoA synthesis leads to a hypoacetylated proteome and parasite death. We previously determined that mitochondrial acetyl-CoA is primarily synthesized from glucose-derived pyruvate by α-ketoacid dehydrogenases.
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- Sexual and reproductive health (SRH) research is vital for creating effective policies that support adolescent girls, but ethical challenges hinder their involvement, especially in low- and middle-income countries (LMICs).
- A study conducted in Tijuana from February to September 2019 included 30 girls aged 16-20, who shared their views on the risks and benefits of participating in studies related to gender-based violence, unintended pregnancy, and STIs.
- Key findings emphasized the importance of customizing consent and incentives for participants, fostering strong researcher-participant relationships, and empowering girls to articulate their sexual health needs to enhance their involvement in SRH research.
The population of Hispanic older adults is growing along with the burden of chronic diseases. This cross-sectional study aims to assess the factors associated with frailty among community-dwelling Hispanic women aged ≥60 years ( = 357) enrolled in the Panama Aging Research Initiative-Health Disparities study of cognitive-functional health of older persons in Panama. Cognitive function was assessed with a neuropsychological test battery.
View Article and Find Full Text PDFBackground: Illicitly manufactured fentanyl (IMF) increases overdose mortality, but its role in infectious disease transmission is unknown. We examined whether IMF use predicts hepatitis C virus (HCV) and human immunodeficiency virus (HIV) incidence among a cohort of people who inject drugs (PWID) in San Diego, California and Tijuana, Mexico.
Methods: PWID were recruited during 2020-2022, undergoing semi-annual interviewer-administered surveys and HIV and HCV serological rapid tests through 2024.