Publications by authors named "G Rameshkumar"
Article Synopsis
- - The study aimed to create a quick and accurate CRISPR-based test called RID-MyC for identifying fungal infections, specifically fungal keratitis, comparing it to traditional diagnostic methods.
- - Conducted with 142 patients in South India, the RID-MyC assay uses advanced molecular techniques to amplify and detect fungal DNA, showing strong agreement with existing diagnostic approaches.
- - Results demonstrated high sensitivity (93.27%) and specificity (89.47%) for diagnosing fungal keratitis, significantly reducing diagnostic time to about 50 minutes, highlighting its potential as an effective diagnostic tool.
Purpose: To study the effect of prophylactic intracameral moxifloxacin (ICM) on microbiological profile and antimicrobial sensitivity of culture-proven postoperative endophthalmitis (POE).
Methods: This study evaluated culture-proven POE diagnosed within 6 weeks of cataract surgery over two periods, period-1 (January 2010-March 2015) and period-2 (April 2015-December 2019), before and after introduction of prophylactic ICM, respectively.
Results: In period-1, 100 cases of culture-positive POE were reported (1 in 4879, 0.
Purpose: The purpose of this study was to study the incidence, demographic features, clinical course, profiling, and management of uncommon species of Pseudomonas keratitis (other than Pseudomonas aeruginosa ) at a tertiary eye care center.
Methods: Thirty cases of culture-proven uncommon species of Pseudomonas keratitis between January 2017 and December 2021 were retrospectively studied. The incidence, demographic and clinical profile, predisposing factors, microbial results, treatment, and visual outcomes were analyzed.
Purpose: Metallo β-lactamases (MβL) production is a worldwide problem, particularly in gram-negative bacteria. As scanty data is available on the prevalence of MBL, the present study is being undertaken to determine the prevalence, antibacterial sensitivity patterns, and molecular characterization of MβL associated resistant genes in gram-negative bacteria isolated from ocular infections.
Material And Methods: At a tertiary eye care center in south India, 359 gram-negative pathogens, 200 isolates from eye infections, and 159 isolates from normal flora of the eye were studied.