Prostitution, condom use, and invasive squamous cell cervical cancer in Thailand.

Cervical cancer is probably caused by a sexually transmitted agent. A case-control study was conducted in three hospitals in Thailand to investigate further the role of male sexual behavior, particularly regarding sexual contacts with prostitutes, in the development of this disease. Data were obtained from interviews with 225 married women with invasive squamous cell cervical carcinoma and 791 hospitalized controls, all of whom reported having only one sexual partner, and from interviews with their husbands.

Monthly injectable steroid contraceptives and cervical carcinoma.

The World Health Organization Collaborative Study of Neoplasia and Steroid Contraceptives is a large multinational hospital-based case-control study of steroid contraceptives and gynecologic, hepatobiliary, and mammary neoplasms. Monthly injectable steroid contraceptives which contained the long-acting progestogen dihydroxyprogesterone acetofenide plus a shorter-acting estrogen (usually estradiol enanthate) were used by women in two of the countries (Chile and Mexico) from which data were collected. In preliminary analyses of data from Chile (1979-1983), a strong association was observed between use of these products and invasive cervical cancer.

Incidence and morbidity of cancer of the cervix in Geneva, Switzerland.

The incidence and mortality rates of invasive carcinoma of the cervix in the state of Geneva, Switzerland, is reported for the time periods 1970-1973 and 1980-1983. A reduction in mortality (7 to 4.3/100,000) occurred as well as a considerable decrease in the overall incidence (20.

Risk factors for invasive cervical cancer and reduction of risk by 'Pap' smears in Thai women.

A case-control study of invasive cervical cancer was conducted in Siriraj Hospital, Thailand, as part of a WHO-sponsored collaborative study of neoplasia and steroid contraceptives. Data from 189 histologically confirmed cases and 1023 randomly selected hospitalized controls who were recruited from October 1979 through March 1983 were analysed to identify risk factors for cervical cancer in Thai women, and to assess the effectiveness of Papanicolaou smears (Pap smears) in preventing invasive cervical cancer in Thailand. Variables that distinguish women at significantly increased risk of invasive cervical cancer, to whom preventive programmes should be directed, include a history of treatment for abnormal vaginal discharge (an indicator of vaginal or cervical infection), a history of venereal disease, and little or no education (an indicator of low socioeconomic status).

Endometrial cytohistology by the pistol-aspiration technique: clinical applicability.

The purpose of this study was to assess the value of the endometrial pistol-aspiration technique as an office procedure for diagnosing corpus uteri cancer in symptomatic and asymptomatic women. Review of 3000 pistol aspirations in symptomatic outpatient women from 1974-1981 confirms that this method, with its high specificity and sensitivity, can be used for such women as a preliminary diagnostic procedure, eliminating risks from anesthesia and curettage as well as the cost of hospitalization. Analysis of resident incident cases shows that 82% were localized to the uterus, and more than 85% of these women were already symptomatic.