Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects.

Background: There is continuous debate whether chlorthalidone (CTD) and hydrochlorothiazide (HCTZ) differ in reducing major cardiovascular events (MACE). HCTZ is prescribed 10 times more commonly than CTD.

Method: A systematic literature search yielded 14 references, including two network meta-analyses of randomized trials with MACE and left ventricular mass as outcomes.

Postural Instability and Seasickness in a Motion-Based Shooting Simulation.

Motion sickness is a problem for many; however, it is especially pressing for military personnel who need to operate in life and death environments. The current study investigated the underlying cause of motion sickness by testing postural instability theory. Subjects experienced realistic motion profiles while performing a virtual reality shooting task and reporting any motion sickness symptoms.

Measuring Lethal Force Performance in the Lab: The Effects of Simulator Realism and Participant Experience.

Objective: The goal of the current study was to compare two types of shooting simulators to determine which is best suited for assessing different aspects of lethal force performance.

Background: Military and law enforcement personnel are often required to make decisions regarding the use of lethal force. A critical goal of both training and research endeavors surrounding lethal force is to find ways to simulate lethal force encounters to better understand behavior in those scenarios.

Obesity-Induced Hypertension: Heavy on the Accelerator.

See Article Fan et al.