Publications by authors named "G R Potts"
Secondary hyperhidrosis is a multifactorial condition that poses unique diagnostic and management challenges. Distinguishing secondary from primary hyperhidrosis remains difficult due to overlapping symptoms. This review consolidates existing evidence on the numerous underlying causes and pathophysiologic mechanisms of secondary hyperhidrosis across various disciplines.
View Article and Find Full Text PDFArticle Synopsis
- Burns can lead to disfigurement, causing both physical scarring and emotional distress due to noticeable pigment changes.
- Treating burn scars can be challenging, often involving painful and invasive procedures.
- This study reports the first successful use of a topical solution (bimatoprost 0.03%) to improve a hypopigmented burn scar, offering a promising noninvasive treatment option.
Targeted protein degradation (TPD) is a therapeutic approach that leverages the cell's natural machinery to degrade targets instead of inhibiting them. This is accomplished by using mono- or bifunctional small molecules designed to induce the proximity of target proteins and E3 ubiquitin ligases, leading to ubiquitination and subsequent proteasome-dependent degradation of the target. One of the most significant attributes of the TPD approach is its proposed catalytic mechanism of action, which permits substoichiometric exposure to achieve the desired pharmacological effects.
View Article and Find Full Text PDFArticle Synopsis
- Recent studies show dermatology residents are satisfied treating skin conditions in people of color, but their comfort levels with hair-related issues specific to these populations are unclear.
- The study surveyed dermatology residents in the U.S. to assess their comfort level and knowledge regarding common hair conditions, especially those affecting individuals with skin of color.
- Results indicated residents felt confident about common conditions but struggled with topics like natural hair care and creating hair regimens, emphasizing the need for better training and diversity in dermatology programs.