Use of Intra-Articular Amphotericin B in the Treatment of Candida parasilosis and albicans in Prosthetic Joint Infections (PJI): A Novel Approach to this Difficult Problem.

Background: Use of intra-articular antibiotics for the treatment of arthroplasty infections has gained some interest over the last few years.

Objective: Some data exists on its use with bacterial arthroplasty infections.

Method: We used intra-articular amphotericin B in an attempt to cure these joint infections and perform a one stage revision.

Vancomycin-resistant Enterococcus faecium osteomyelitis: successful treatment with quinupristin-dalfopristin.

Vancomycin-resistant enterococci (VRE) have recently emerged as an increasing concern in the management of severe infections. Treatment of these life-threatening infections has been limited to quinupristin-dalfopristin and, more recently, linezolid therapy. We report the first case, to our knowledge, of vancomycin-resistant Enterococcus faecium vertebral osteomyelitis treated successfully with quinupristin-dalfopristin.

Anatomic analysis of pedicle cortical and cancellous diameter as related to screw size.

The effective thoracic and lumbar pedicle diameter as related to screw size for that pedicle was studied in six fresh-frozen human cadaver spines. Measurements of the pedicle were obtained before screw insertion using axial and coronal reformatted computed tomographic (CT) images, as well as graduated sounding of the pedicle. After sequentially loading each pedicle with increasingly larger screws, measurements were taken of the outer cortical diameters.