Publications by authors named "G R Farmer"

: Coronavirus-19 (COVID-19) vaccines represent a significant milestone in the fight against coronavirus disease. Ongoing post-marketing surveillance and research are crucial for ensuring vaccine safety and effectiveness, aiding public health planning. : Our retrospective cohort study included Albertans five years and older and vaccinated with at least one dose of an approved COVID-19 vaccine between 14 December 2020 and 30 April 2022.

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Purpose: In March 2020, a 1-week ultrahypofractionated adjuvant breast radiation therapy schedule, 26 Gy in 5 fractions, and telehealth were adopted to reduce the risk of COVID-19 for staff and patients. This study describes real-world 1-year late toxicity for ultrahypofractionation (including a sequential boost) and patient perspectives on this new schedule and telehealth workflows.

Methods And Materials: Consecutive patients were enrolled between March and August 2020.

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Objectives: To examine the psychosocial impact of the COVID-19 pandemic on patients with a diagnosis of diabetes mellitus (DM).

Methods: Semi-structured interviews were conducted with 31 individuals with DM attending a diabetes clinic to determine the impact of the COVID-19 restrictions on anxiety and depressive symptoms, social and occupational functioning and quality of life. Anxiety symptoms were correlated with functioning, quality of life and diabetes self-management.

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Article Synopsis
  • Angiotensin II (ANG II) affects the central nervous system, but the presence of a brain-specific renin-angiotensin system (RAS) is still debated.
  • Researchers used modified Chinese hamster ovary cells to measure ANG II release from brain slices of rats, finding that its release is mostly dependent on renin and ACE-1 but might have alternative pathways, particularly in renin knockout rats.
  • Findings show that ANG II release increases after chronic intermittent hypoxia, indicating that a unique tissue-specific RAS in the brain could be affected in models of conditions like sleep apnea.
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Objectives: Post-marketing surveillance of sotrovimab's effect during implementation in the Canadian population is limited.

Methods: The study used a propensity score-matched retrospective cohort design. Follow-up began between the periods of December 15, 2021 and April 30 2022.

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