Publications by authors named "G R Dagenais"
Article Synopsis
- Rivaroxaban 2.5 mg twice daily combined with aspirin was more effective than aspirin alone for preventing serious cardiovascular events in patients with stable coronary artery disease (CAD) or peripheral artery disease (PAD).
- A cost-analysis over a 23-month follow-up showed that while the total costs for the combination treatment were higher ($7,426), it provided an extra 1.17 quality-adjusted life years (QALYs), resulting in a favorable incremental cost-effectiveness ratio (ICER) of $23,295/QALY.
- The study concludes that using rivaroxaban with aspirin is a cost-effective strategy in the U.S., making it a valuable option for managing cardiovascular health in these patients.
Objective: Arterial stiffness and exposure to psychosocial work-related factors increase the risk of developing cardiovascular disease. However, little is known about the relationship between psychosocial work-related factors and arterial stiffness. We aimed to examine this relationship.
View Article and Find Full Text PDFBackground: Psychosocial stressors at work, like job strain and effort-reward imbalance (ERI), can increase coronary heart disease (CHD) risk. ERI indicates an imbalance between the effort and received rewards. Evidence about the adverse effect of combined exposure to these work stressors on CHD risk is scarce.
View Article and Find Full Text PDFAims: To develop a healthy diet score that is associated with health outcomes and is globally applicable using data from the Prospective Urban Rural Epidemiology (PURE) study and replicate it in five independent studies on a total of 245 000 people from 80 countries.
Methods And Results: A healthy diet score was developed in 147 642 people from the general population, from 21 countries in the PURE study, and the consistency of the associations of the score with events was examined in five large independent studies from 70 countries. The healthy diet score was developed based on six foods each of which has been associated with a significantly lower risk of mortality [i.
Objective: To evaluate the effects of fixed dose combination (FDC) medications on cardiovascular outcomes in different age groups in an individual participant meta-analysis of three primary prevention randomised trials.
Methods: Participants at intermediate risk (17.7% mean 10-year Framingham Cardiovascular Risk Score), randomised to FDC of two or more antihypertensives and a statin with or without aspirin, or to their respective control, were followed up for 5 years.