Publications by authors named "G R Berry"
Background: Windsock deformities, though rare, represent a severe form of valvular aneurysm distinguished by localized balloon-like protrusions of the leaflet body. Here, we present a compelling case of windsock mitral valve (MV) formation subsequent to incompletely managed aortic valve (AV) endocarditis. The case is illustrated through radiographic, intraoperative, and histopathologic images.
View Article and Find Full Text PDFIdentifying population-level relationships between predators and their prey is often predicated on having reliable population estimates. Camera-trapping is effective for surveying terrestrial wildlife, but many species lack individually unique natural markings that are required for most abundance and density estimation methods. Analytical approaches have been developed for producing population estimates from camera-trap surveys of unmarked wildlife; however, most unmarked approaches have strict assumptions that can be cryptically violated by survey design characteristics, practitioner choice of input values, or species behavior and ecology.
View Article and Find Full Text PDFBackground: Proteomic phenotyping can provide insights into rejection pathophysiology, novel biomarkers, and therapeutic targets.
Methods: Within the prospective, multicenter Genomic Research Alliance for Transplantation study, 181 proteins were evaluated from blood drawn at the time of endomyocardial biopsy; protein fold change, logistic regression, and pathway analyses were conducted, with protein discovery adjusted for a 5% false discovery rate.
Results: Among 104 adult heart transplant patients (31% female sex, 53% Black race, median age 52 y), 74 had no rejection, 18 developed acute cellular rejection (ACR), and 12 developed antibody-mediated rejection (AMR).
Article Synopsis
- A study investigated the safety and efficacy of combining regorafenib and low-dose methotrexate for patients with advanced -mutant NSCLC, as there are limited treatment options available beyond G12C inhibitors.
- The study included 18 patients, revealing a median progression-free survival of 3.7 months and a median overall survival of 10.4 months, with a 16.7% objective response rate.
- The treatment caused notable toxicity, leading to dose adjustments and discontinuations; consequently, the study did not meet its primary goal of improving progression-free survival.
Article Synopsis
- - This text discusses a case of neonatal babesiosis, a rare condition caused by a parasite transmitted by ticks, which was discovered during a typical evaluation for suspected sepsis in a newborn.
- - A full-term male neonate presenting with fever was found to have Babesia microti parasites in his blood, and maternal history showed prior signs of thrombocytopenia and anemia linked to the same parasite.
- - The case emphasizes the need for healthcare providers to consider babesiosis as a possible diagnosis in feverish neonates, especially in areas where the disease is common, and to review maternal health records and blood tests thoroughly.