Publications by authors named "G R Amin"
Introduction Anti-tumor necrosis factor alpha (TNFα) therapies have revolutionized the management of Crohn's disease (CD). However, they increase the risk of viral reactivation, particularly hepatitis B virus (HBV). This study aims to define the HBV serological profiles of patients with CD who are candidates for biological therapy, identifying profiles at potential risk for reactivation or exacerbation following immunosuppressive treatment.
View Article and Find Full Text PDFIntroduction: Recent literature continues to demonstrate the successful role of large-bore aspiration catheters in thrombus ingestion during mechanical thrombectomy. However catheter-to-microwire step-off and distal navigation are ongoing challenges in thrombectomy. A new to market 0.
View Article and Find Full Text PDFArticle Synopsis
- - Smoking, especially chronic smoking, poses a significant health risk by increasing the chances of heart-related diseases and causing damage to the heart's structure and function through oxidative stress and endothelial dysfunction.
- - This study examines how chronic cigarette smoke interacts with the oral contraceptive ethinylestradiol in premenopausal females, revealing that their combination leads to negative changes in heart structure, such as larger left ventricular size and increased heart mass.
- - Results indicate that this combination triggers an inflammatory response, with elevated inflammatory markers and collagen deposition, suggesting it may lead to heart conditions similar to dilated cardiomyopathy.
Article Synopsis
- Enterovirus infections can impact the central nervous system, causing conditions like meningitis and encephalitis, and this study aimed to detail these infections for Moroccan patients.
- Conducted from January 2021 to March 2023 at Ibn Sina University Hospital, the study analyzed 1,479 cerebrospinal fluid samples, finding enterovirus in just 19 patients, mostly young children and males.
- Common symptoms included fever and headache, and while many cases showed lymphocytic patterns in CSF analysis, some results could mimic bacterial infections, highlighting the importance of using multiplex PCR for accurate diagnosis.
The effect of probiotic supplementation on non-alcoholic fatty liver disease (NAFLD) fibrosis score in patients attending a tertiary hospital clinic in Cairo, Egypt.
BMC Gastroenterol
October 2024
Article Synopsis
- - Non-alcoholic fatty liver disease (NAFLD) involves fat buildup in the liver without alcohol use, potentially leading to more severe liver issues like cirrhosis or liver cancer; this study evaluated if probiotics could help improve the NAFLD fibrosis score.
- - In a randomized controlled trial, 50 NAFLD patients were split into two groups: one received probiotics with lifestyle changes, while the other only got dietary advice; the trial lasted 12 weeks with regular follow-ups.
- - Results showed the probiotic group had significant improvements in liver enzymes and body mass index (BMI), but no change in the NAFLD fibrosis score compared to the standard treatment group, suggesting more research is needed for conclusive