It is indisputable that high-resolution ultrasound (US) is the diagnostic gold standard for the evaluation of superficial parotid gland diseases. It is a dynamic, quick, simple, easily available, cost-effective, noninvasive procedure, with absence of ionizing radiation examination that can be performed safely and in special categories of patients such as pregnant women and children. It is widely accepted that on US, benign tumors have clear, smooth and well-defined borders, homogeneous hypoechoic parenchyma and a defined distribution of vessels.
View Article and Find Full Text PDFBackground: Herein, we evaluated the attributable fraction (AF) of human papillomavirus (HPV)-mediated (HPV+) oropharyngeal carcinomas (OPCs) in Greece over a recent calendar period.
Patients And Methods: ORPHEAS, a retrospective, observational, multicenter, cross-sectional study with prospective recruitment, included adult patients with OPC in 2017-2022, each of them with a high-quality, treatment-naïve tumor specimen. The primary endpoint was the HPV-AF, defined as combined positivity for p16 (p16) overexpression and HPV DNA presence by central laboratory testing, among included patients.
Objectives: Optimal timing of tracheostomy in severe traumatic brain injury (TBI) is unknown due to lack of clinical trials. We emulated a target trial to estimate the effect of early vs. delayed tracheostomy strategy on functional outcome of patients with severe TBI.
View Article and Find Full Text PDFLaryngocele, a dilation of the laryngeal saccule, is an uncommon and benign air-filled lesion that expands upwards into the ventricle of Morgagni. A unilateral growth within the larynx that is in communication with the laryngeal lumen typically signals its presence. The exact cause of the disorder remains uncertain, although there are three main theories which suggest congenital reasons, increased pressure in the larynx, or mechanical obstruction of the ventricle of Morgagni.
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