SERS-PLSR Analysis of Vaginal Microflora: Towards the Spectral Library of Microorganisms.

The accurate identification of microorganisms belonging to vaginal microflora is crucial for establishing which microorganisms are responsible for microbial shifting from beneficial symbiotic to pathogenic bacteria and understanding pathogenesis leading to vaginosis and vaginal infections. In this study, we involved the surface-enhanced Raman spectroscopy (SERS) technique to compile the spectral signatures of the most significant microorganisms being part of the natural vaginal microbiota and some vaginal pathogens. Obtained data will supply our still developing spectral SERS database of microorganisms.

[Penicillinase production by Neisseria gonorrhoeae strains isolated from the patients of Dermatology and Wenerology Clinic, Warsaw Medical University in 2006 - 2009].

In recent years the resistance of Neisseria gonorrhoeae to antibiotics is increasing in many countries. The aim of the study was to investigate penicillinase production by Neisseria gonorrhoeae strains isolated from the patients of Clinic of Dermatology and Wenerology WUM in a period between 2006 - 2009. We cultured the bacteria on Roiron medium and we used the iodometric test or BBL Cefinase discs to detect penicillinase.

[Incidence and the results of treatment of beta-lactamase-positive gonorrhea with spectinomycin (trobicin)].

Beta-lactamase-positive gonorrhoea was rather sporadic in Poland. In spring 1988 a marked rise was observed in the proportion of therapeutic failures in the treatment of gonorrhoea with procaine penicillin (4.8 million u) with probenecid among patient treated in the outpatient clinic of the Venereology Institute in Warsaw.

[The course of early syphilis in morphine base-dependent rabbits].

Eleven rabbits made dependent on morphine base were observed which were infected with syphilis studying the clinical and serological course of the infection. The control group comprised five non-dependent rabbits infected with syphilis. After 30 days from the infection all animals were given procaine penicillin in daily doses of 75,000 mu/kg.