Publications by authors named "G Properzi"

Proprotein convertase subtilisin/kexin type 9 (PCSK9)-related discoveries of the turn of the century have translated into substantial novelty in dyslipidemia treatment in the last 5 years. With chronic preventable atherosclerotic cardiovascular diseases (ASCVD) representing an epidemic of morbidity and mortality worldwide, low-density lipoprotein cholesterol (LDL-c) reduction represents a public health priority. By overcoming two major statin-related issues, namely intolerance and ineffectiveness, PCSK9 inhibitors have offered a safe and effective option in selected clinical settings where LDL-c reduction is required.

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Introduction: Elevated serum uric acid (SUA) levels are associated with increased cardiovascular risk.

Objective: To evaluate the association between SUA levels and cardiometabolic parameters.

Materials And Methods: SUA levels and metabolic parameters were evaluated in 139 subjects, divided into low (<5 mg/dl) and high SUA group (≥5 mg/dl).

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Since tendon injuries and tendinopathy are a growing problem, sometimes requiring surgery, new strategies that improve conservative therapies are needed. Platelet-rich plasma (PRP) seems to be a good candidate by virtue of its high content of growth factors, most of which are involved in tendon healing. This study aimed to evaluate if different concentrations of platelets in PRP have different effects on the biological features of normal human tenocytes that are usually required during tendon healing.

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Objective: To investigate the relationship among serum uric acid levels and metabolic syndrome.

Materials And Methods: Anthropometric parameters, serum uric acid and metabolic parameters were evaluated in 139 subjects.

Results: Serum uric acid levels were significantly higher in subjects with than without metabolic syndrome (p < 0.

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