Publications by authors named "G Prabhakaran"
This study investigated gaze behavior during visuo-cognitive-motor tasks with a change of movement direction in glaucoma patients and healthy controls. Nineteen glaucoma patients (10 females, 9 males) and 30 healthy sighted controls (17 females, 13 males) participated in this cross-sectional study. Participants performed two visuo-cognitive-motor tasks with a change of movement direction: (i) the "Speed-Court-Test" that involved stepping on different sensors in response to a visual sign displayed on either a large or small screen (165″ and 55″, respectively); (ii) the "Trail-Walking-Test" that required walking to 15 cones labeled with numbers (1-8) or letters (A-G) in an alternately ascending order.
View Article and Find Full Text PDFTreadmill-walking impairs visual function in early glaucoma and elderly controls.
Graefes Arch Clin Exp Ophthalmol
November 2024
Aims: Impaired vision is an additional risk factor in elderly for falls. We investigated the hypothesis that treadmill (TM) walking affects visual function in both healthy elderly and those with early-moderate visual dysfunction due to glaucoma.
Methods: Thirty healthy controls (HC) aged 64-83 years and 18 glaucoma patients (GLA) aged 62-82 years participated in this cross-sectional study.
Purpose: To investigate gait kinematics during single- and dual-task walking in glaucoma patients compared with healthy controls.
Methods: Nineteen glaucoma patients (10 females, 9 males) and 30 healthy controls (17 females, 13 males) participated in this cross-sectional study. Spatiotemporal gait parameters (e.
Article Synopsis
- Albinism is a condition affecting pigmentation and visual system structure, prompting research into anatomical changes for improved diagnostics, particularly using a CNN called CHIASM-Net.
- This CNN was designed to detect malformations in the optic chiasm from MRI images, using data from a significant number of control and albinism cases, and evaluated through rigorous statistical methods.
- CHIASM-Net showed promising results with 85% accuracy and identified key areas in the optic chiasm as influential for its predictions, highlighting the potential of CNNs for visual pathway analysis in diagnostics.
Article Synopsis
- In low- and middle-income countries, diarrhoeal diseases, mainly caused by bacteria like cholera and enterotoxigenic E. coli (ETEC), are a leading cause of child mortality.
- Cholera vaccines utilizing the cholera toxin component provide short-term protection against ETEC, which lacks a specific vaccine.
- A study on a prototype cholera vaccine, MyChol, showed it was safe and effective in mice, helping to neutralize ETEC toxins and reduce intestinal colonization after exposure to a lethal ETEC strain.