The maximum growth temperature and human pathogenicity of psychrotrophic aeromonads.

Determination of the maximum growth temperature of Aeromonas strains isolated from clinical material and endowed with pronounced propensity for adhesion to intestinal cells has demonstrated that all strains still grow at 39 degrees C, with this holding true for the majority of strains also at 40 degrees C. Since Aeromonas isolated obtained from water evidence to a large extent a markedly lower maximum growth temperature, the 39 degrees C growth criterion is a characteristic of Aeromonas strains isolated from clinical material.

Radiation therapy in stage III ovarian cancer following surgery and chemotherapy: prognostic factors, patterns of relapse, and toxicity: a preliminary report.

Twenty patients with FIGO stage III epithelial ovarian cancer who had undergone maximum cytoreductive surgery (including pelvic and paraaortic lymph node dissection) and combination chemotherapy (4-10 cycles, median 6) were treated with irradiation to the abdomen and pelvis with 30 Gy followed by diaphragmatic/paraaortic and pelvis boost fields to 42 and 51.6 Gy, respectively. Second-look laparotomy was not performed.

Intraoperative plus external beam irradiation in nonresectable lung cancer: assessment of local response and therapy-related side effects.

Since 1987, 24 patients with inoperable non-small-cell lung cancer (NSCLC), stage T1-3 N0-2 M0, have undergone lymph node dissection and intraoperative radiation therapy (IORT) to the primary with 10-20 Gy. Patient selection criteria were nonresectability based on severe cardiorespiratory impairment, no radiological evidence of distant metastases and a Karnofsky performance status of greater than 80. In 18 patients the IORT procedure was followed by an external beam radiation series (EBR) including the tumor with 46 Gy and the regional lymph nodes with 46/56 Gy.

Intraoperative radiation therapy combined with external irradiation in nonresectable non-small-cell lung cancer: preliminary report.

Twenty-one patients with nonresectable non-small-cell lung cancer (15 squamous-cell, 4 adeno, 2 large-cell; T1-T3, N0-N2, all M0) underwent lymph node dissection and intraoperative irradiation of the tumor (IORT) with doses between 10 and 20 Gy (energies: 7 to 20 MeV electron beam). Postoperatively, 46-56 Gy external beam irradiation (8 or 23 MeV photon beam) were delivered to the mediastinum and 46 Gy to the tumor bearing area. Fifteen patients were available for follow-up investigations.

[Intraoperative radiotherapy (IORT) at the Graz University Clinics: results of a pilot study on non-small cell lung carcinoma].

A pilot study was undertaken during which 15 patients with non-small cell pulmonary carcinomas were exposed to an intraoperative irradiation; twelve out of them were submitted to an additional percutaneous photon therapy. The criteria used to select these patients were functional inoperability, exclusion of remote metastases, and a Karnofsky index greater than 70. Central and peripheral tumors of the stages T1-3, N0-2 were included into the study after histological confirmation of the diagnosis.